Hey friends,
I want to highlight another upcoming longevity event, and one that I’d actually clear my calendar for.
Vitalist Bay is May 14–17, at Lighthaven in Berkeley and the lineup this year is serious.
We’re talking 100+ leaders working on aging from every angle: the biology, the biotech, the AI, the policy, the money. Joe Betts-LaCroix (Retro Biosciences), Morgan Levine (Altos Labs), Michael Snyder (Stanford’s Center for Genomics and Personalized Medicine), Jean Hebert (ARPA-H), and that’s just the start of the speaker list.
What I love about Vitalist Bay specifically is the venue. Lighthaven is built for intimate workshops, salons, actual nooks where you can go deep with someone instead of exchanging business cards and moving on.
Register at vitalistbay.com, and use code NFC25 for 25% off your ticket.
In this episode, I sit down with Dr. Katrin Dreissigacker, a plastic surgeon turned longevity architect and founder of Epigenedit, to explore why hyperbaric oxygen therapy may be one of the most overlooked tools in longevity science.
We talk about her journey from a small village in East Germany to becoming known as the “Queen of Needles,” how she reversed markers of biological aging, improved her VO2 max in midlife, and why oxygen, mitochondria, skin health, resilience, and reinvention are all deeply connected.
Key Topics:
Hyperbaric oxygen therapy and its role in longevity
Innovations in aesthetic medicine and needling techniques
The impact of oxygen saturation on aging and skin health
Biomarkers of aging and how hyperbaric oxygen influences them
The use of peptides and biohacking for healthspan extension
Timestamps:
00:00 – Reversing Biological Age? The Power of Oxygen
00:30 – From East Germany to Elite Medicine
02:30 – Why She Chose Medicine (Unexpected Path)
04:05 – What Is Aesthetic Medicine (Beyond Vanity)
06:30 – “Queen of Needles” & Revolutionizing Fillers
09:30 – First Encounter with Hyperbaric Oxygen Therapy
12:00 – From Pandemic to Longevity Innovation
14:30 – Why She Built Her Own HBOT Chamber
16:45 – Can HBOT Really Improve VO2 Max?
18:30 – How HBOT Actually Works (Simple Explanation)
21:10 – Mild vs Medical HBOT: What’s the Difference?
23:45 – What It Improves: Sleep, Recovery & Aging
25:00 – How Often Should You Do HBOT?
27:30 – Risks, Side Effects & Common Fears
30:30 – The Real Benefits (Why You Don’t Feel It Immediately)
34:50 – Skin, Collagen & The ‘Glow Effect’
37:10 – Who Should NOT Use HBOT?
39:00 – Most Underrated Longevity Tool?
41:30 – Peptides: Hype or Breakthrough?
43:40 – Biggest Misconceptions About HBOT
45:30 – Most Overused Aesthetic Treatment Today
47:00 – Daily Habits for Longevity & Energy
48:15 – What Shows Up on Your Skin the Most?
51:00 – Reinvent Yourself at Any Age
ABOUT DR. KATRIN DREISSIGACKER: Physician, pioneer in aesthetic medicine and Co-Founder of EpigenEdit, believes ageing is not something to fight but something to design. After three decades at the forefront of aesthetics, she now focuses on longevity science, using tools such as mild hyperbaric oxygen therapy to support cellular regeneration, performance, and vitality from within.
RESOURCES MENTIONED:
www.epigenedit.com
Instagram: @epigenedit_europe / @katrin_dreissigacker
LinkedIn: www.linkedin.com/in/katrin-dreissigacker
Katrin’s individual practice: www.katrin-dreissigacker.com
ABOUT NINA’S NOTES: Nina’s Notes explores the intersection of longevity science, neuroscience, and human optimization. Hosted by Nina Patrick, PhD in pharmaceutical sciences and longevity researcher, each episode translates cutting-edge research into actionable insights for living longer, better.
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