#163: 🌈 Are Psychedelics The Fountain of Youth?
Exploring The Latest Research Where Psychedelics and Longevity Intersect
Hey friends,
This is the last hot & fresh newsletter from Nina’s Notes in 2025. I will take a much needed three week break and come back January 14, 2026.
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Today I am sharing a previously recorded talk I gave for Longevity Wednesday’s on November 12, 2025 and for the Female Founders Breakfast on December 4, 2025.
Every time I’ve shared this info, the audience shared that they have learned something new and felt inspired. I hope you feel the same.
Love from Lisbon,
Nina
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#163: 🌈 Are Psychedelics The Fountain of Youth?
Watch the episode here:
In this conversation, I cover the emerging science on psychedelics. Not the hype, but the data.
How these compounds interact with the brain, reopen windows of neuroplasticity, and appear to influence aging, neurodegenerative disease, mental health, trauma, and resilience in ways we’re only beginning to understand.
I walk through studies looking at psychedelics in neurodegenerative disease, stroke recovery, and end-of-life care, specifically improvements in Parkinson’s, life extension in cells and mice, and cancer patients losing their fear of death.
The thread tying all of this together is simple but uncomfortable: longevity isn’t just about adding years to the body. It’s about tending to the nervous system, the mind, and the stories we carry.
If we want to live longer and better, we may need to stop treating biology and psychology as separate systems, and start designing a more integrated, humane approach to aging.
Timestamps:
00:00 Introduction to Epigenetics and Longevity
02:42 The Intersection of Psychedelics and Longevity
05:36 Understanding the Hallmarks of Aging
08:51 Mental Health, Neuroplasticity, and Aging
11:45 Psychedelics and Neurodegenerative Diseases
14:46 Psychedelics in Stroke Recovery
17:33 Psychedelics and Trauma Healing
20:30 Psychedelics in End-of-Life Care
23:41 The Future of Longevity and Psychedelics
Listen to the episode on 🔴YouTube, 🟢 Spotify, 🟣 Apple Podcasts, 🟠Substack Podcasts.
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Edited by Wright Time Publishing
Compelling framing of neuroplasticity as a longevity lever. The connection between reopening critical periods and cellular aging pathways is something most longevity research overlooks becuase we tend to separate neuroscience and gerontology into different buckets. I'm curious how the dose-response curve looks for maintaning cognitive flexibilty without triggering oxidative stress from repeated activation, that trade-off probaly matters for actual healthspan extension.